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Society for Neuroscience's 49th Annualmeeting

会议日期： 2019年10月19日

会议地点：美国/伊利诺斯/芝加哥

主办单位：美国神经科学学会

RTS,S/AS01疟疾疫苗（英文）

2024年01月16日

关键词： 2023全球十大工程成就

’s Best Papers of 2015

《环境科学与工程前沿（英文）》 2016年第10卷第4期 doi: 10.1007/s11783-016-0858-6

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Anion-exchange membrane direct ethanol fuel cells: Status and perspective

T.S. Zhao, Y.S. Li, S.Y. Shen

《能源前沿（英文）》 2010年第4卷第4期页码 443-458 doi: 10.1007/s11708-010-0127-5

摘要： Direct ethanol fuel cells (DEFCs) are a promising carbon-neutral and sustainable power source for portable, mobile, and stationary applications. However, conventional DEFCs that use acid proton-exchange membranes (typically Nafion type) and platinum-based catalysts exhibit low performance (i.e., the state-of-the-art peak power density is 79.5 mW/cm at 90°C). Anion-exchange membrane (AEM) DEFCs that use low-cost AEM and non-platinum catalysts have recently been demonstrated to yield a much better performance (i.e., the state-of-the-art peak power density is 160 mW/cm at 80°C). This paper provides a comprehensive review of past research on the development of AEM DEFCs, including the aspects of catalysts, AEMs, and single-cell design and performance. Current and future research challenges are identified along with potential strategies to overcome them.

关键词： fuel cell direct ethanol fuel cells anion-exchange membrane ethanol oxidation reaction oxygen reduction reaction cell performance

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Astrocytes in depression and Alzheimer’s disease

《医学前沿（英文）》 2021年第15卷第6期页码 829-841 doi: 10.1007/s11684-021-0875-0

摘要： Astrocytes are an abundant subgroup of cells in the central nervous system (CNS) that play a critical role in controlling neuronal circuits involved in emotion, learning, and memory. In clinical cases, multiple chronic brain diseases may cause psychosocial and cognitive impairment, such as depression and Alzheimer’s disease (AD). For years, complex pathological conditions driven by depression and AD have been widely perceived to contribute to a high risk of disability, resulting in gradual loss of self-care ability, lower life qualities, and vast burden on human society. Interestingly, correlational research on depression and AD has shown that depression might be a prodrome of progressive degenerative neurological disease. As a kind of multifunctional glial cell in the CNS, astrocytes maintain physiological function via supporting neuronal cells, modulating pathologic niche, and regulating energy metabolism. Mounting evidence has shown that astrocytic dysfunction is involved in the progression of depression and AD. We herein review the current findings on the roles and mechanisms of astrocytes in the development of depression and AD, with an implication of potential therapeutic avenue for these diseases by targeting astrocytes.

关键词： astrocytes depression Alzheimer’s disease roles mechanisms

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FESE’s Best Papers of 2020

《环境科学与工程前沿（英文）》 2021年第15卷第3期 doi: 10.1007/s11783-021-1424-4

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基于马尔可夫到达过程的两级可修备件（S-1，S）库存优化模型

陈童,黎放,狄鹏

《中国工程科学》 2015年第17卷第5期页码 113-119

摘要：，采用马尔可夫到达过程（MAP）描述备件需求规律，考虑有限维修设施的情况，假设故障件维修时间、备件运输时间以及采购时间均服从phase-type（PH）分布，建立了一种描述能力更强、解析计算性更好的（S-1，S）库存优化模型，并推导出系统缺货量分布函数；然后通过算例演示了模型的优化效果，验证了模型的正确性和适用性。

关键词：（S-1，S）库存策略；两级库存；可修备件；马尔可夫到达过程

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New Year’s Message for 2022

《环境科学与工程前沿（英文）》 2022年第16卷第1期页码 14-14 doi: 10.1007/s11783-022-1538-3

摘要： 2022 marks the 15th anniversary of the journal of Frontiers of Environmental Science & Engineering (FESE). To date, FESE has received more than 5500 submissions from more than 80 countries and our acceptance rate is ~20%. FESE has also been providing a communication and development platform by increasing its editorial board, organizing conferences, and setting up awards. We are grateful for the support from authors, reviewers, readers, and editorial colleagues to jointly make FESE an internationally recognized journal in the Environmental Science and Engineering field. FESE is becoming an important and irreplaceable forum on environmental issues. Nowadays, environmental issues have attracted tremendous attention and they call for solutions to combat pollution, to achieve carbon neutrality, to tackle climate change, and to promote sustainable development. Accordingly, research is tackling more complex challenges and FESE is conveying knowledge and technological solutions to address these challenges. FESE will implement several new initiatives in 2022. First, FESE will further increase the quality of its publications and its services to the Environmental Science and Engineering community. Second, FESE will publish articles in a more timely fashion by publishing them on a monthly basis. Third, we will introduce a new article style, “Opinion,” that will broaden our perspectives and focus. Fourth, we have been launching the first Young Talent Award which will recognize promising investigators. 2022 will certainly be a year full of passion and expectations. Hereby, we hope that FESE will march toward a higher level with the hard work from editorial board members and editorial office, the continuous support from authors and reviewers, and the close collaborations among Chinese Academy of Engineering, Tsinghua University, Higher Education Press, Springer, and other organizations. Finally, we wish you all a happy, healthy, and fruitful 2022!

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FESE’s Best Papers of 2021

《环境科学与工程前沿（英文）》 2022年第16卷第6期 doi: 10.1007/s11783-022-1561-4

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FESE’s Best Papers of 2022

《环境科学与工程前沿（英文）》 2023年第17卷第6期 doi: 10.1007/s11783-023-1678-0

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Exergy analysis and simulation of a 30MW cogeneration cycle

Nikhil Dev, Samsher, S. S. Kachhwaha, Rajesh Attri

《机械工程前沿（英文）》 2013年第8卷第2期页码 169-180 doi: 10.1007/s11465-013-0263-9

摘要：

Cogeneration cycle is an efficient mean to recover the waste heat from the flue gases coming out of gas turbine. With the help of computer simulation, design parameters may be selected for the best performance of cogeneration cycle. In the present work a program is executed in software EES on the basis of mathematical modelling described in paper to study cogeneration cycle performance for different parameters. Results obtained are compared with the results available in literature and are found in good agreement with them. Real gas and water properties are inbuilt in the software. Results show that enthalpy of air entering the combustion chamber is higher than that of the flue gases at combustion chamber outlet. For different operative conditions, energy and exergy efficiencies follow similar trends; although, exergy efficiency values are always lower than the corresponding energy efficiency ones. From the results it is found that turbine outlet temperature (TIT) of 524°C is uniquely suited to efficient cogeneration cycle because it enables the transfer of heat from exhaust gas to the steam cycle to take place over a minimal temperature difference. This temperature range results in the maximum thermodynamic availability while operating with highest temperature and highest efficiency cogeneration cycle. Effect of cycle pressure ratio (CR), inlet air temperature (IAT) and water pressure at heat recovery steam generator (HRSG) inlet on the 30 MW cogeneration cycle is also studied.

关键词： Cogeneration cycle air compressor HRSG gas turbine regenerator CR IAT

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Development of environmental management system in China's financial sector

CHANG Miao, PENG Lijuan, WANG Shiwen

《环境科学与工程前沿（英文）》 2008年第2卷第2期页码 172-177 doi: 10.1007/s11783-008-0032-x

摘要： The establishment of the environmental management system in the financial sector can be effectively promoted through the introduction of the environmental protection concept and its implementation by the financial sector. The impact of a sustainable development system on the sector is analyzed in this article from three aspects: environmental risk assessment, financing support for environmental protection projects, and financial services to environmentally friendly corporations and individuals. Influential factors on the development of the environmental management system in China’s financial sector are discussed from the perspective of various entities such as financial institutions, financial regulation authorities, environmental protection departments, corporations, and the public. It is pointed out that China’s financial sector is now in the transitional phase from a defensive attitude to a preventive attitude. Strengthening governmental guidance, the supervision of regulators as well as public awareness of environmental protection should be used to enhance the initiative in the development of the environmental management system in the Chinese financial sector.

关键词： perspective s financial financial ’ s transitional

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et’s disease in a Chinese population

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《医学前沿（英文）》 2012年第6卷第4期页码 354-359 doi: 10.1007/s11684-012-0234-2

摘要：

Beh?et’s disease is defined as a multisystemic inflammatory disease. Although the precise pathogenesis and etiology is still a mystery, accumulating evidence shows that genetic variants of immune-related genes have a profound influence on the development of Beh?et’s disease. To explore the genetic factors for Beh?et’s disease, our group investigated the association of Beh?et’s disease with multiple immune response genes and has identified multiple Beh?et’s disease-related immunoregulatory pathways in the Chinese Han population. A large number of gene polymorphisms were studied including STAT4, IL23R, CD40, CCR1/CCR3, STAT3, OPN, IL17, JAK2, MCP-1, CTLA4, PD-1, PD-L1, PD-L2, TGRBR3, CCR6, PTPN22, FCRL3, IRF5, SUMO4 and UBAC2. Significant associations were found between Beh?et’s disease and STAT4, IL23R, CD40, CCR1/CCR3, STAT3, MCP-1, TGFBR3, FCRL3, SUMO4, UBAC2. These genetic predisposition studies support an important role for both lymphocyte differentiation as well as ubiquitination pathways. These findings are helpful in elucidating the pathogenesis of Beh?et’s disease and hopefully will allow the development of novel treatment regimes.

关键词： Beh?et’s disease SNPs immune gene genetic study